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Notes from clinical data practice

Practical writing on data standards, validation, reporting, and the changing shape of regulatory submissions.

Data Standards · 8 min read

Building ADaM datasets with the admiral package

A modular, derivation based approach to ADaM that improves traceability and cuts the rework that comes with late data changes.

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Submissions · 7 min read

What the R submission pilots mean for sponsors

The regulatory pilots that brought R based packages and interactive review applications to the FDA, and what they change for filing teams.

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Validation · 9 min read

Standing up a validated computing environment

What it takes to run R and Python for regulated analytics, from package qualification through audit trails and reproducibility.

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