The pharmaverse

A curated set of packages covering the path from raw data to clinical reporting. It lets sponsors collaborate on shared tooling instead of each rebuilding the same components.

R submission pilots

The R Consortium submission working group has run a series of pilots with the FDA, delivering tables, datasets, and interactive review applications through the electronic gateway.

Contribution and qualification

We report issues, submit fixes upstream, and run the validation needed to use these packages safely inside audit ready workflows.

Packages we work with

A representative set of the open packages our teams use across data standards, reporting, and submissions.

admiralADaM

Modular, traceable creation of ADaM analysis datasets.

sdtm.oakSDTM

Builds standardized SDTM domains from collected data.

rtablesTLG

Flexible, submission grade clinical trial tables.

ternTLG

Analysis functions and standardized clinical output.

TplyrTLG

A grammar for clinical summary statistics.

tealShiny

Framework for interactive clinical data review.

xportrSubmission

Writes compliant transport files for delivery.

pkgliteSubmission

Packages R code into a submittable text artifact.

metacoreMetadata

Holds machine readable dataset specifications.

metatoolsMetadata

Utilities for working with metadata standards.

sdtmchecksSDTM

Quality checks and validation for SDTM datasets.

tidytlgTLG

Templated, end to end table and figure production.

Open packages need qualification before they can be trusted in a filing. We pair adoption with validation, so the tooling carries the evidence a regulated process requires.

Considering a move to open clinical tooling?

We can help you adopt these packages and qualify them for your validated environment.

Talk to us